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Amyotrophic lateral sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS)

Review over Amyotrophic Lateral Sclerosis (ALS) and the First FDA-Approved Drug for Treatment of ALS:   Introduction Amyotrophic lateral sclerosis (ALS) is a progressive nervous system disease that affects nerve cells which control voluntary muscle movement. Patient’s sensory functions or mental faculties doesn’t changed through ALS. ALS is considered as a progressive disease. There is […]

Understanding Type 2 Diabetes and Medications for Management

Type 2 diabetes

  Type 2 diabetes is a prevalent chronic condition, that affects millions of people worldwide. It occurs when the body cannot effectively use the insulin it produces, leading to elevated blood sugar levels. Proper management of Type 2 diabetes is crucial to prevent complications and improve the quality of life for those diagnosed. In addition […]

Molnupiravir

Molnupiravir

  Molnupiravir may be effective against the omicron sub-variant BA.5 According to a study published in the New England Journal of Medicine on Thursday, a team led by a professor of virology at the University of Tokyo, found that small-molecule antiviral drug molnupiravir curbed virus activity in cultured monkey cells infected with the highly contagious […]

Soft Tissue Sarcoma

Soft Tissue Sarcoma

Tyrosine kinase inhibitors in Soft Tissue Sarcomas treatment   Sarcomas are a group of rare mesenchymal malignant cancers which arise from transformed cells of the mesenchymal connective tissue, and are challenging to be treated. The majority of sarcomas are soft tissue sarcomas (STSs; 75%) and this heterogeneous group of tumors is further comprised of gastrointestinal […]

Dapagliflozin in Patients with Type 2 Diabetes

Dapagliflozin

Benefits of Dapagliflozin When in Patients with Type 2 Diabetes Abstracts Dapagliflozin reduces the risk of cardiovascular and kidney outcomes in patients with type 2 diabetes whether or not they were also taking various cardiovascular (CV) medications. The study that has published in JAMA Cardiology, explored whether the diuretic and antihypertensive effects of dapagliflozin, a sodium-glucose cotransporter […]

Breast Cancer Awareness Month

Breast Cancer Awareness October is Breast Cancer Awareness Month, an annually campaign to raise awareness of this disease.Yet, for many, Breast Cancer Awareness Month is also a difficult reminder of their personal experience with breast cancer and the many patients we have lost to this disease. As of 2020, there were 2.26 million worldwide cases of breast […]

Comprehending Heart Failure and Its Therapeutic Approaches

Heart Failure

  Comprehending Heart Failure and Its Therapeutic Approaches Introduction to Heart Failure Heart failure is a complex and chronic medical condition that affects millions of individuals worldwide. Despite the term sounding quite severe, it does not mean that the heart has completely ceased to function. Instead, heart failure indicates that the heart is not pumping […]

Benefits of Crizotinib in Advanced NSCLC

Crizotinib

Benefits of Crizotinib in Advanced Non-Small Cell Lung Cancer (NSCLC)   Abstract: Non-small-cell lung cancer has poor prognosis and low survival rates, providing a strong rationale for the development of new treatment strategies. Advanced non-small cell lung cancer (NSCLC) Patients have few effective treatment options, only about a third of these patients experience tumor shrinkage with standard […]

EGFR-TKI

EGFR-TKI

The Clinical Efficacy of Combinatorial Therapy of EGFR-TKI and Crizotinib in Overcoming MET amplification-mediated Resistance   Abstract Treatment of non-small cell lung cancer harboring epidermal growth factor receptor activating mutation with EGFR-TKIs has achieved great success, yet faces the development of acquired resistance as the biggest obstacle to long-period disease remission in the clinic. MET or c-MET gene amplification has […]

Arthritis

World AUTO immune & AUTO inflammatory Arthritis Day    This event historically unites thousands of people in 60+ countries worldwide to drive global awareness and education about the Autoimmune and Auto-inflammatory diseases that include inflammatory-driven arthritis. There is no other globally program focused on Autoimmune Arthritis and associated diseases that is as big and has […]