Amyotrophic lateral sclerosis (ALS)
Review over Amyotrophic Lateral Sclerosis (ALS) and the First FDA-Approved Drug for Treatment of ALS: Introduction Amyotrophic lateral sclerosis (ALS) is a progressive nervous system disease that affects nerve cells which control voluntary muscle movement. Patient’s sensory functions or mental faculties doesn’t changed through ALS. ALS is considered as a progressive disease. There is […]
Dapagliflozin in Patients with Type 2 Diabetes
Benefits of Dapagliflozin When in Patients with Type 2 Diabetes Abstracts Dapagliflozin reduces the risk of cardiovascular and kidney outcomes in patients with type 2 diabetes whether or not they were also taking various cardiovascular (CV) medications. The study that has published in JAMA Cardiology, explored whether the diuretic and antihypertensive effects of dapagliflozin, a sodium-glucose cotransporter […]
Breast Cancer Awareness Month
Breast Cancer Awareness October is Breast Cancer Awareness Month, an annually campaign to raise awareness of this disease.Yet, for many, Breast Cancer Awareness Month is also a difficult reminder of their personal experience with breast cancer and the many patients we have lost to this disease. As of 2020, there were 2.26 million worldwide cases of breast […]
Comprehending Heart Failure and Its Therapeutic Approaches
Comprehending Heart Failure and Its Therapeutic Approaches Introduction to Heart Failure Heart failure is a complex and chronic medical condition that affects millions of individuals worldwide. Despite the term sounding quite severe, it does not mean that the heart has completely ceased to function. Instead, heart failure indicates that the heart is not pumping […]
Understanding Type 2 Diabetes and Medications for Management
Type 2 diabetes is a prevalent chronic condition, that affects millions of people worldwide. It occurs when the body cannot effectively use the insulin it produces, leading to elevated blood sugar levels. Proper management of Type 2 diabetes is crucial to prevent complications and improve the quality of life for those diagnosed. In addition […]
Molnupiravir
Molnupiravir may be effective against the omicron sub-variant BA.5 According to a study published in the New England Journal of Medicine on Thursday, a team led by a professor of virology at the University of Tokyo, found that small-molecule antiviral drug molnupiravir curbed virus activity in cultured monkey cells infected with the highly contagious […]
Soft Tissue Sarcoma
Tyrosine kinase inhibitors in Soft Tissue Sarcomas treatment Sarcomas are a group of rare mesenchymal malignant cancers which arise from transformed cells of the mesenchymal connective tissue, and are challenging to be treated. The majority of sarcomas are soft tissue sarcomas (STSs; 75%) and this heterogeneous group of tumors is further comprised of gastrointestinal […]
Tofacitinib the first FDA approved JAK inhibitor
An overview of Tofacitinib, the first FDA approved JAK inhibitor, and its Indications Introduction Tofacitinib is a type of drug known as Janus kinase JAK inhibitor. Tofacitinib is a small molecule, not a protein; therefore, causing the formation of neutralizing anti-drug antibodies related to therapeutic proteins, and immunogenicity is not expected to occur. It works by […]
increase Risk of Developing Diabetes
COVID-19 infection even mild ones may increase Risk of Developing Diabetes A recent study followed people with mild COVID-19 to analyze whether or not they had an increased risk of developing diabetes. As a sway, they also tracked individuals with an acute upper respiratory tract infection (AURI). The researchers concluded that individuals with mild […]
Benefits of lenalidomide in hematological malignancies
Abstract Lenalidomide is an immunomodulatory drug, which has effect against most of the hematological malignancies. Apart from its immunomodulation, it has other properties such as anti-proliferation and anti-angiogenesis. It is not only effective in myeloma and myelodysplastic syndromes, recent studies show its effectiveness on newly diagnosed and relapsed/refractory lymphomas as well. Addition of lenalidomide to […]