EGFR-TKI
The Clinical Efficacy of Combinatorial Therapy of EGFR-TKI and Crizotinib in Overcoming MET amplification-mediated Resistance Abstract Treatment of non-small cell lung cancer harboring epidermal growth factor receptor activating mutation with EGFR-TKIs has achieved great success, yet faces the development of acquired resistance as the biggest obstacle to long-period disease remission in the clinic. MET or c-MET gene amplification has […]
Arthritis
World AUTO immune & AUTO inflammatory Arthritis Day This event historically unites thousands of people in 60+ countries worldwide to drive global awareness and education about the Autoimmune and Auto-inflammatory diseases that include inflammatory-driven arthritis. There is no other globally program focused on Autoimmune Arthritis and associated diseases that is as big and has […]
Overview of Thyroid Cancer
Targeted therapies used in the Treatment of Thyroid Cancer Introduction Thyroid cancer is a rare type of cancer that affects the thyroid gland; it might not cause any symptoms at first. But as it progreses, the signs and symptoms get appeared, including swelling in your neck, difficulty swallowing, and voice changes. There are four main types […]
Monkeypox
The current monkeypox situation is consistently evolving and subject to change. The aim of this Disease Outbreak News is to raise public awareness, inform readiness and response efforts, and provide technical guidance for immediate needed actions. Outbreak at glance Since 13 May 2022, cases of monkeypox have been reported from 12 Member States that are […]
World MS Day
About World MS Day MS is an inflammatory demyelinating condition. It is caused by damage to myelin, a fatty material that insulates nerves. In MS, the loss of myelin affects the way nerves conduct electrical impulses to and from the brain. Symptoms can include blurred vision, weak limbs, tingling sensations, unsteadiness, memory problems, and […]
Therapy for Hepatocellular Carcinoma
Advances of Targeted Therapy for Hepatocellular Carcinoma Hepatocellular carcinoma (HCC) is categorized as one of the common and fatal malignancies, which is an important global health problem. The clinical applicability of traditional surgery and other loco-regional therapies is limited, and these therapeutic strategies are far from satisfactory in improving the outcomes of advanced HCC. Through […]
Mantle Cell Lymphoma
Recent Results Show ibrutinib-Based Combination Regimen Significantly Reduced the Risk of Disease Progression or Death in Older Patients with Newly Diagnosed Mantle Cell Lymphoma The Janssen Pharmaceutical Company today announced primary results from the Phase 3 SHINE study, which demonstrated that the combination of once-daily oral ibrutinib plus bendamustine-rituximab (BR) and rituximab maintenance significantly […]
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) Global Day Annually the International ALS/MND Associations celebrates 21 June as the global day of recognition of ALS/MND, a disease that affects people in every country of the world. ALS/MND is a global problem. It doesn’t discriminate on the basis of ethnicity or region, there are patients all over the world. For every […]
Hepatocellular carcinoma
Hepatocellular carcinoma (HCC) Liver cancer is a global health challenge, with an estimated incidence of >1 million patients by 2025. Primary liver cancer is one that started in the liver. There are 5 main types. The type of liver cancer depends on the cell type that the cancer started in. If cancer began somewhere else […]
WHO Backs Molnupiravir for High-Risk Covid-19 Patients
The ninth update of WHO’s guideline on COVID-19 therapeutics includes a conditional recommendation on molnupiravir, a new antiviral medicine. This is the first oral antiviral medicine which is included in the treatment guidelines for COVID-19, as this is a new medicine, there is little safety information; WHO recommends active monitoring for drug safety, along […]