Benefits of lenalidomide in hematological malignancies
Abstract Lenalidomide is an immunomodulatory drug, which has effect against most of the hematological malignancies. Apart from its immunomodulation, it has other properties such as anti-proliferation and anti-angiogenesis. It is not only effective in myeloma and myelodysplastic syndromes, recent studies show its effectiveness on newly diagnosed and relapsed/refractory lymphomas as well. Addition of lenalidomide to […]
Melonama Monday, May Is Melanoma
Melonama Monday, May Is Melanoma Awareness Month It is Good to Know about the Dark Side of the Sun Melonama Skin cancer, including melanoma as well basal and squamous cell carcinomas, is the most common cancer type.The rates of melanoma, the most dangerous form of skin cancer, have been rising for the past few decades.Melanoma […]
Benefits of Crizotinib in Advanced NSCLC
Benefits of Crizotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Abstract: Non-small-cell lung cancer has poor prognosis and low survival rates, providing a strong rationale for the development of new treatment strategies. Advanced non-small cell lung cancer (NSCLC) Patients have few effective treatment options, only about a third of these patients experience tumor shrinkage with standard […]
EGFR-TKI
The Clinical Efficacy of Combinatorial Therapy of EGFR-TKI and Crizotinib in Overcoming MET amplification-mediated Resistance Abstract Treatment of non-small cell lung cancer harboring epidermal growth factor receptor activating mutation with EGFR-TKIs has achieved great success, yet faces the development of acquired resistance as the biggest obstacle to long-period disease remission in the clinic. MET or c-MET gene amplification has […]
Arthritis
World AUTO immune & AUTO inflammatory Arthritis Day This event historically unites thousands of people in 60+ countries worldwide to drive global awareness and education about the Autoimmune and Auto-inflammatory diseases that include inflammatory-driven arthritis. There is no other globally program focused on Autoimmune Arthritis and associated diseases that is as big and has […]
Overview of Thyroid Cancer
Targeted therapies used in the Treatment of Thyroid Cancer Introduction Thyroid cancer is a rare type of cancer that affects the thyroid gland; it might not cause any symptoms at first. But as it progreses, the signs and symptoms get appeared, including swelling in your neck, difficulty swallowing, and voice changes. There are four main types […]
Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present) One of the most common and deadliest disease on record is lung cancer. According to estimates with increasing incidence each year, about 85% of lung cancer cases are non-small cell lung cancer type, and about […]
Type 2 Diabetes Mellitus
Overview of Type 2 Diabetes Mellitus Type 2 diabetes mellitus is the most common type of diabetes, in which the blood glucose, is too high. This chronic condition may lead to disorders of the circulatory, nervous and immune systems, and affects your everyday life. In type 2 diabetes there are mainly 2 associated problems; body […]
Parsian Pharama Review of CDK4/6 Inhibitors Citing to the Recent Articles
Parsian pharama review of CDK4-6 inhibitors citing to the recent articles One of the most common cancers among women is Breast cancer. Sometimes the average risk of developing breast cancer in a woman in the United States in her lifespan is about 13%. More than 70% of breast cancer cases are Hormone receptor–positive (HR+) types, […]
US FDA Approved Empagliflozin
The U.S. FDA Approved Empagliflozin for Wider Range of Patients with Heart Failure Abstracts: On February 24, 2022, The U.S. FDA approved an expanded indication for empagliflozin which is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, to reduce the risk of Cardiovascular (CV) death and Heart failure (HF) hospitalization in adults with HF with reduced or […]