Marginal Zone Lymphoma (MZL)
Quick overview of Marginal Zone Lymphoma (MZL): Marginal zone lymphoma (MZL) which is also called marginal zone B-cell lymphoma, is a group of B-cell non-Hodgkin lymphomas, which at first is formed in certain areas (the marginal zones) of lymph tissue. MZL is the second most common indolent non-Hodgkin’s lymphoma (iNHL); and account for approximately eight […]
Waldenstrom Macroglobulinemia (WM)
Introduction of Waldenstrom Macroglobulinemia (WM) Waldenstrom Macroglobulinemia (WM) is a non-Hodgkin lymphoma (NHL), in which the cancer cells make large amounts of an abnormal protein (called a macroglobulin). Another name for this subtype of NHL cancers is lymphoplasmacytic lymphoma. This condition is a rare indolent B-cell lymphoma that occurs in less than two percent of […]
Graft-versus-Host Disease (GvHD)
Quick Review over Graft-versus-Host Disease (GvHD) Introduction: Graft-versus-Host Disease (GvHD) is a common complication because of a transplantation using donor; this complication occurs when the donor’s immune system (the graft) recognizes the patient’s organs and tissues (the host) as unfamiliar cells that should be destroyed. This complication is triggered by a type of white blood cell […]
Cancer Statistics
Cancer statistics According to the American Cancer Society’s annual estimate of 2021, there will be 1898160 new cases and 608570 deaths caused by that in the United States. In generally, due to improvements in various facets of humans’ lives, including availability of different instruments for diagnosing mortality rate has shrunk from its peak in 1991 […]
Multiple sclerosis (MS)
Quick Review over Multiple sclerosis (MS) Multiple sclerosis (MS) is a lifelong, and often disabling disease which affects the central nervous system (brain and spine). In multiple sclerosis, scattered patches of the protective myelin covering of the nerve fibers in the CNS are damaged or destroyed. This leads to inflammation and loss of myelin which […]
Protein Tyrosine Kinases:Their Roles and Their Targeting in Leukemia
Protein tyrosine kinases superfamily definition A large group of enzymes that speeding up protein phosphorylation and controlling multiple signaling incidents are titled as Protein tyrosine kinases, which represents a complicated system and is wrapped up by of 518 members. Based on their ability to phosphorylate either tyrosine or serine and threonine residues, they are classified into two main […]
Disease modifying therapies (DMTs)
Quick Review Over Disease Modifying Therapies (DMTs) For Multiple Sclerosis Introduction: Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of the CNS. Although there is no curable options for MS, a number of medications also called, disease modifying therapies, or DMTs, have been approved to treat MS. Permanent damage to the central nervous system can […]
Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present) One of the most common and deadliest disease on record is lung cancer. According to estimates with increasing incidence each year, about 85% of lung cancer cases are non-small cell lung cancer type, and about […]
Type 2 Diabetes Mellitus
Overview of Type 2 Diabetes Mellitus Type 2 diabetes mellitus is the most common type of diabetes, in which the blood glucose, is too high. This chronic condition may lead to disorders of the circulatory, nervous and immune systems, and affects your everyday life. In type 2 diabetes there are mainly 2 associated problems; body […]
Parsian Pharama Review of CDK4/6 Inhibitors Citing to the Recent Articles
Parsian pharama review of CDK4-6 inhibitors citing to the recent articles One of the most common cancers among women is Breast cancer. Sometimes the average risk of developing breast cancer in a woman in the United States in her lifespan is about 13%. More than 70% of breast cancer cases are Hormone receptor–positive (HR+) types, […]