Mechanism Of Action:
It’s a selective inhibitor of factor Xa (FXa), and is an inhibitor of free FXa and prothrombinase activity, and indirectly inhibits platelet aggregation induced by thrombin.
Indication:
- Reduction of Risk of Stroke and Systemic Embolism in Non-valvular Atrial Fibrillation (NVAF)
- Treatment of Deep Vein Thrombosis (DVT) & Pulmonary Embolism (PE)
- Reduction in the Risk of Recurrence of DVT and/or PE
- Prophylaxis of DVT Following Hip or Knee Replacement Surgery
- Prophylaxis of Venous Thromboembolism in Acutely Ill Medical Patients at Risk for Thromboembolic Complications Not At High Risk of Bleeding
- Reduction of Risk of Major Cardiovascular Events in Patients with Chronic Coronary Artery Disease (CAD) or Peripheral Artery Disease (PAD)
- Treatment of venous thromboembolism, and Prophylaxis of recurrent venous thromboembolism in in pediatric patients.
