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Rivaroxaban

Rivaroxaban

IUPAC name:

5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide

CAS No.

366789-02-8

Molecular Weight:

435.88g.mol−1

Molecular Formula:

C19H18ClN3O5S

Granule:

Available-Ready to press

Explationtion

Mechanism Of Action:

It’s a selective inhibitor of factor Xa (FXa), and is an inhibitor of free FXa and prothrombinase activity, and indirectly inhibits platelet aggregation induced by thrombin.

Indication:

  1. Reduction of Risk of Stroke and Systemic Embolism in Non-valvular Atrial Fibrillation (NVAF)
  2. Treatment of Deep Vein Thrombosis (DVT) & Pulmonary Embolism (PE)
  3. Reduction in the Risk of Recurrence of DVT and/or PE
  4. Prophylaxis of DVT Following Hip or Knee Replacement Surgery
  5. Prophylaxis of Venous Thromboembolism in Acutely Ill Medical Patients at Risk for Thromboembolic Complications Not At High Risk of Bleeding
  6. Reduction of Risk of Major Cardiovascular Events in Patients with Chronic Coronary Artery Disease (CAD) or Peripheral Artery Disease (PAD)
  7. Treatment of venous thromboembolism, and Prophylaxis of recurrent venous thromboembolism in in pediatric patients.
information
Category: Cardiovascular
January 21, 2024
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