Mechanism Of Action: Ruxolitinib belongs to the drug class called janus kinase inhibitors (JAK inhibitors). It acts as an inhibitor of the JAK1 and JAK2

Mechanism Of Action: Olaparib functions as an inhibitor of poly(ADP-ribose) polymerase, effectively impeding the repair of single-strand DNA breaks. This mechanism leads to synthetic lethality

Mechanism Of Action: Crizotinib is a tyrosine kinase receptor inhibitor. It inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor (HGFR, c-MET), and Recepteur d’Origine

Mechanism Of Action: Osimertinib is an EGFR tyrosine kinase inhibitor that binds to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) that

Mechanism Of Action: Vandetanib is a selective and potent inhibitor of VEGFR (vascular endothelial growth factor receptor), EGFR (epidermal growth factor receptor) and RET (RE-arranged

Mechanism Of Action: Dasatinib, at nanomolar concentrations can inhibit the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on

Mechanism Of Action: Dasatinib, at nanomolar concentrations can inhibit the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on

Mechanism Of Action: Regorafenib is an inhibitor of multiple membrane-bound and intracellular kinases involved in normal cellular functions and in pathologic processes including, oncogenesis, tumor

Mechanism Of Action: Pazopanib is a second-generation multi-targeted tyrosine kinase inhibitor against vascular endothelial growth factor receptor-1, -2, and -3, platelet-derived growth factor receptor-alpha, platelet-derived

Mechanism Of Action: Exhibits immunomodulatory properties. Activates and increases number of T cells and NK cells Increases number of NKT cells Inhibits pro-inflammatory cytokines (e.g.,