Mechanism Of Action:
Enoxaparin, a low molecular weight heparin (LMWH), works primarily by activating antithrombin III, which in turn inhibits factor Xa and IIa (thrombin). This inhibition prevents the formation of fibrin clots, thereby exerting its anticoagulant effect. Enoxaparin is commonly used to prevent and treat deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as to prevent ischemic complications in unstable angina and non-Q-wave myocardial infarction.
Indications
Prevention of deep vein thrombosis (DVT): Used to prevent blood clots in the veins, especially after surgeries like hip or knee replacement.
Treatment of deep vein thrombosis (DVT): Helps dissolve existing blood clots in the veins.
Prevention of pulmonary embolism (PE): Prevents blood clots from traveling to the lungs, which can be life-threatening.
Treatment of pulmonary embolism (PE): Treats existing blood clots in the lungs.
Prevention of ischemic complications in unstable angina: Reduces the risk of heart-related complications in patients with chest pain due to reduced blood flow to the heart.
Prevention of ischemic complications in non-Q-wave myocardial infarction: Lowers the risk of heart complications in patients who have had a type of heart attack without a specific ECG change.
Prevention of ischemic complications in ST-segment elevation myocardial infarction (STEMI): Used in combination with other treatments to reduce heart complications in patients with a severe type of heart attack.
