APIXABAN

IUPAC name:

1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide

CAS No.

503612-47-3

Molecular Weight:

459.5g.mol−1

Molecular Formula:

C25H25N5O4

Granule:

Available-Ready to press

Mechanism Of Action:

It’s a highly selective and reversible direct inhibitor of free and clot-bound factor Xa, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. FXa catalyzes the conversion of prothrombin to thrombin.

Indication:

Prophylaxis of venous thromboembolism following knee or hip replacement surgery
Treatment of Deep Vein Thrombosis (DVT) & Pulmonary Embolism (PE)
Prophylaxis of recurrent DVT and PE
Prophylaxis of stroke and systemic embolism in non-valvular atrial fibrillation and at least one risk factor (such as previous stroke or transient ischemic attack, symptomatic heart failure, diabetes mellitus, hypertension, or age 75 years and over)

information

Category: Cardiovascular

January 21, 2024

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Cas No: 2023788-19-2

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Mechanism Of Action: Lenvatinib is classified as a receptor tyrosine kinase (RTK) inhibitor that effectively suppresses the kinase activities of vascular endothelial growth factor (VEGF)

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