It is released by mast cells and basophils during allergic reactions and helps to dilate blood vessels, allowing immune cells to reach the site of infection or injury. However, when histamine levels become too high, it can lead to symptoms such as itching, hives, headaches, and gastrointestinal issues. This condition is known as histamine intolerance, which occurs when the body is unable to break down histamine efficiently.
Medications that target histamine are commonly used to treat allergic reactions and other conditions involving excessive histamine release. Antihistamines, such as diphenhydramine (Benadryl) and cetirizine (Zyrtec), work by blocking histamine receptors, thereby reducing symptoms like itching, swelling, and redness. There are also medications that can inadvertently increase histamine levels or interfere with its breakdown, leading to histamine intolerance. These include certain antibiotics, pain medications, and gastrointestinal drugs.

Parsian Pharmaceutical Co. is a leading company in Iran specializing in the production of high-quality and cost-effective generic Active Pharmaceutical Ingredients (APIs). With a strong focus on research and development, Parsian Pharma is continuously expanding its portfolio to include innovative products across various treatment segments. By entering the field of histamine-related medications.