IUPAC name
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione;hydrate
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione;hydrate
847871-99-2
536.5 g·mol−1
C26H28N6O7
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· Exhibits immunomodulatory properties.
Activates and increases number of T cells and NK cells
Increases number of NKT cells
Inhibits pro-inflammatory cytokines (e.g., TNF-a, and IL-6) by monocytes
· Inhibits cell proliferation and induces apoptosis of tumor cells in vitro and inhibition of tumor growth in vivo, leading to a decrease in tumor burden.
· Inhibits angiogenesis by reducing levels of VEGF, TNF-a, and IL-6.