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Dimethyl fumarate

Dimethyl fumarate

IUPAC name:

dimethyl (E)-but-2-enedioate

CAS No.

624-49-7

Molecular Weight:

144.12 g.mol−1

Molecular Formula:

C6H8O4

Granule:

Explationtion

Mechanism Of Action:

It acts centrally by activating the nuclear factor erythroid 2 related factor 2 (Nrf2) transcriptional pathway, which regulates enzymes that reduce oxidative stress. And may enhance the Nrf2 transcriptional pathway within the CNS, but this is unproven.

Indication:

Dimethyl fumarate is indicated for the treatment of relapsing types of MS including: clinically isolated syndrome (CIS), relapsing-remitting disease, and active secondary progressive disease, in adult patients.

information
Category: Multiple Sclerosis
January 21, 2024
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