IUPAC name:
(Z)-2-Cyano-3-hydroxy-but-2-enoic acid-(4trifluoromethylphenyl)-amide
CAS No.
163451-81-8
Molecular Weight:
270.211 g.mol−1
Molecular Formula:
C12H9F3N2O2
Granule:
It’s a selective and reversible inhibitor of dihydro-orotate dehydrogenase, which is a key mitochondrial enzyme in the de novo pyrimidine synthesis pathway, leading to a reduction in proliferation of activated B and T lymphocytes without causing cell death.
Teriflunomide is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
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