Letrozole

ONCOLOGY
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Letrozole is a aromatase Inhibitor. It is used in the treatment of breast cancer. inhibits the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization

Imatinib mesylate

ONCOLOGY
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Imatinib is a tyrosine kinase inhibitor. It inhibits the activity of the  Bcr-Abl tyrosine kinase (TK)

Sorafenib tosylate

ONCOLOGY
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Sorafenib is a tyrosine kinase inhibitor, Angiogenesis Inhibitor and VEGF inhibitor. It inhibits multiple intracellular (c-CRAF, BRAF and mutant BRAF) and cell surface kinases 

 

Nilotinib.HCl.H2O

ONCOLOGY
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Nilotinib is a tyrosine kinase inhibitor. It inhibits the ABL tyrosine kinase activity of the BCR-ABL oncoprotein both in cell lines and in primary Philadelphia-chromosome positive leukaemia cells

 

Erlotinib.HCl

ONCOLOGY
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Erlotinib is a tyrosine kinase inhibitor, epidermal growth factor receptor inhibitor, EGFR inhibitor and EGF receptor inhibitor. It inhibits the intracellular phosphorylation of tyrosine kinase associated with the epidermal

Sunitinib malate

ONCOLOGY
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Sunitinib is a multi-receptor tyrosine kinase (RTK) inhibitor. It inhibits CD117 (c-KIT) , the receptor tyrosine kinase and all receptors for platelet-derived growth factor (PDGF-Rs) and vascular endothelial growth factor receptors

Gefitinib

ONCOLOGY
Gefitinib
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Gefitinib is a tyrosine kinase inhibitor. It inhibits the epidermal growth factor receptor (EGFR) tyrosine kinase that binds to the adenosine triphosphate (ATP)-binding site of the enzyme

Palbociclib

ONCOLOGY
Palbociclib
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Palbociclib is a cyclin-dependent kinase 4/6 inhibitor or CDK4/6 inhibitor.it is a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, that acts by binding to the ATP pocket with an IC50

Ibrutinib

ONCOLOGY
Ibrutinib
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Ibrutinib is a burton’s tyrosine kinase inhibitor. it forms a covalent bond with a cysteine residue in the BTK active site, leading to inhibition of BTK enzymatic activity

Lenalidomide

ONCOLOGY
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Lenalidomide inhibits proliferation and induces apoptosis of certain hematopoietic tumor cells including multiple myeloma, mantle cell lymphoma

 

Pazopanib.HCl

ONCOLOGY
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Pazopanib is a multi-receptor tyrosine kinase inhibitor. It inhibits multi-target tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor receptors (VEGFR) -1, -2, and -3, platelet-derived growth factor

Regorafenib

ONCOLOGY
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Regorafenib is a multiple receptor tyrosine kinase inhibitor. It inhibits the activity of RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2,TIE2, DDR2, Trk2A, Eph2A, RAF-1, BRAF, BRAF 

Dasatinib.H2O

ONCOLOGY
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Dasatinib is a tyrosine kinase inhibitor. It inhibits BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ.

 

Dasatinib anhydrous

ONCOLOGY
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Dasatinib is a tyrosine kinase inhibitor. It inhibits BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ

 

VANDETANIB

ONCOLOGY
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Tyrosine kinase inhibitor (TKI) with selective activity against RET, VEGFR-2, and EGFR; TKI inhibition blocks angiogenesis and cellular proliferation

 

OSIMERTINIB

ONCOLOGY
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Osimertinib is kinase inhibitor of the epidermal growth factor receptor (EGFR), which binds irreversibly to certain mutant forms of 

CRIZOTINIB

ONCOLOGY
crizotinib
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Crizotinib is a tyrosine kinase receptor inhibitor. More specifically, it inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor.

Empagliflozin

Anti-diabetic
Empagliflozin
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Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose

 

Dapagliflozin

Anti-diabetic
Dapagliflozin
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Dapagliflozin is a Sodium-glucose cotransporter 2 (SGLT2) inhibitor. It reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion

Linagliptin

Anti-diabetic
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Linagliptin is a competitive, reversible DPP-4 inhibitor. Inhibition of this enzyme slows the breakdown of GLP-1 and glucose-dependent insulinotropic polypeptide

Teriflunomide

Multiple Sclerosis
Teriflunomide
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Teriflunomide is a pyrimidine synthesis inhibitor. It is an immunomodulatory agent with anti-inflammatory properties that selectively and reversibly inhibits the mitochondrial enzyme dihydroorotate dehydrogenase 

Dimethyl fumarate

Multiple Sclerosis
Dimethyl fumarate
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Dimethyl fumarate is an anti-inflammatory. It can activate the transcription factor (Nuclear factor erythroid-derived 2)-related factor 2 (Nrf2) pathway

 

Fingolimod.HCl

Multiple Sclerosis
Fingolimod.HCl
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Fingolimod is a sphingosine l-phosphate receptor modulator. It is metabolized by sphingosine kinase to the active metabolite, fingolimod-phosphate. 

 

Rivaroxaban

Cardiovascular
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Rivaroxaban is a direct Factor Xa Inhibitor. It inhibits free FXa and prothrombinase activity

 

APIXABAN

Cardiovascular
APIXABAN
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Apixaban is a selective inhibitor of factor Xa. It does not require anti thrombin III for antithrombotic activity. Apixaban inhibits free

 

Favipiravir

Covid 19
Favipiravir
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Favipiravir is an antiviral agent. the active favipiravir-RTP selectively inhibits RNA polymerase and prevents replication of the viral genome

 

Molnupiravir 

Covid 19
molnupiravir
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Molnupiravir inhibits the replication of the SARS-CoV-2 virus, the causative agent of COVID-19

Riluzole

Central nervous
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Riluzole is an antiglutamate. motor neurons, made vulnerable through either genetic predisposition or environmental factors, are injured by glutamate so riluzole inhibits  glutamate release

Tofacitinib citrate

Anti-rheumatic
Tofacitinib citrate
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Tofacitinib is a janus kinase inhibitor. JAKs are intracellular enzymes which transmit signals arising from cytokine or growth factor-receptor interactions. 

Roxadustat

Anti-Anemic
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Roxadustat is the first in a new class of treatments, HIF-PH inhibitors that promote erythropoiesis, or red blood cell production, through increased