{"id":2813,"date":"2024-02-03T11:33:29","date_gmt":"2024-02-03T12:33:29","guid":{"rendered":"https:\/\/parsianpharma.com\/or\/?post_type=product&#038;p=2813"},"modified":"2024-03-03T20:33:23","modified_gmt":"2024-03-03T17:03:23","slug":"dabrafenib-mesylate","status":"publish","type":"product","link":"https:\/\/parsianpharma.com\/fa\/product\/dabrafenib-mesylate\/","title":{"rendered":"\u062f\u0627\u0628\u0631\u0627\u0641\u0646\u06cc\u0628 \u0645\u0632\u06cc\u0644\u0627\u062a"},"content":{"rendered":"<div id=\"row-2057601535\">\n<div id=\"col-918350547\">\n<div id=\"row-1892044485\" class=\"row row-full-width align-middle align-center\">\n<div id=\"col-1710115834\" class=\"col small-12 large-12\">\n<div class=\"col-inner\">\n<p>\u0698\u0646 BRAF \u00a0\u062f\u0633\u062a\u0648\u0631\u0627\u0644\u0639\u0645\u0644\u200c\u0647\u0627\u06cc\u06cc \u0628\u0631\u0627\u06cc \u0633\u0627\u062e\u062a \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 BRAF \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u062f\u0647\u062f .\u067e\u0631\u0648\u062a\u0626\u06cc\u0646BRAF \u0633\u0631\u06cc\u0646\/\u062a\u0631\u0626\u0648\u0646\u06cc\u0646 \u06a9\u06cc\u0646\u0627\u0632\u200c\u0647\u0627 \u0647\u0633\u062a\u0646\u062f \u060c \u0627\u06cc\u0646 \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 \u0641\u0633\u0641\u0631 \u0645\u0648\u062c\u0648\u062f \u0628\u0631 \u0631\u0648\u06cc \u0633\u0631\u06cc\u0646 \u0648 \u062a\u0631\u0626\u0648\u0646\u06cc\u0646 \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 \u0647\u0627\u06cc \u0633\u0644\u0648\u0644 \u00a0\u0647\u062f\u0641 \u0631\u0627 \u06a9\u0627\u062a\u0627\u0644\u06cc\u0632 \u200c\u0645\u06cc \u200c\u06a9\u0646\u062f \u0648 \u0622\u062f\u0646\u0648\u0632\u06cc\u0646 \u062a\u0631\u06cc \u0641\u0633\u0641\u0627\u062a (ATP) \u00a0\u0622\u0646 \u0631\u0627 \u0628\u0647 \u0622\u062f\u0646\u0648\u0632\u06cc\u0646 \u062f\u06cc \u0641\u0633\u0641\u0627\u062a (ADP) \u062a\u0628\u062f\u06cc\u0644 \u0645\u06cc\u06a9\u0646\u062f \u06a9\u0647 \u062f\u0631 \u0645\u0633\u06cc\u0631 \u0633\u06cc\u06af\u0646\u0627\u0644\u06cc\u0646\u06af RAS-RAF-MAPK\u060c \u0645\u0633\u06cc\u0631\u06cc \u06a9\u0647 \u062f\u0631 \u0631\u0634\u062f \u0648 \u062a\u0642\u0633\u06cc\u0645 \u0633\u0644\u0648\u0644\u06cc \u0646\u0642\u0634 \u0645\u0647\u0645\u06cc \u062f\u0627\u0631\u062f. \u0686\u0646\u062f\u06cc\u0646 \u0646\u0648\u0639 \u062c\u0647\u0634 \u0645\u062e\u062a\u0644\u0641 BRAF \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u062f \u06a9\u0647 BRAF7600 E(\u06cc\u06a9 \u0648\u0627\u0644\u06cc\u0646 \u0628\u0627 \u06cc\u06a9 \u06af\u0644\u0648\u062a\u0627\u0645\u06cc\u06a9 \u0627\u0633\u06cc\u062f \u062f\u0631 \u0645\u0648\u0642\u0639\u06cc\u062a 600 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646 \u0645\u06cc\u0634\u0648\u062f) \u0648 BRAF7600 K \u0628\u06cc\u0634\u062a\u0631\u06cc\u0646 \u0634\u06cc\u0648\u0639 \u0631\u0627 \u062f\u0627\u0631\u0646\u062f. \u0627\u06cc\u0646 \u062c\u0647\u0634 \u200c\u0647\u0627 \u0628\u0627\u0639\u062b \u0645\u06cc\u0634\u0648\u062f \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 \u0628\u0647 \u0635\u0648\u0631\u062a \u0645\u062f\u0627\u0645 \u0641\u0639\u0627\u0644 \u0634\u0648\u0646\u062f \u0648 \u0645\u0646\u062c\u0631\u0628\u0647 \u0631\u0634\u062f \u0648 \u062a\u0642\u0633\u06cc\u0645 \u0633\u0644\u0648\u0644\u06cc \u0628\u06cc \u0631\u0648\u06cc\u0647 \u06af\u0631\u062f\u062f. \u062c\u0647\u0634 BRAF7600E \u0627\u063a\u0644\u0628 \u062f\u0631 \u0633\u0631\u0637\u0627\u0646 \u0647\u0627\u06cc \u0645\u0644\u0627\u0646\u0648\u0645 \u060c\u0631\u06cc\u0647 \u0648 \u0633\u0631\u0637\u0627\u0646 \u0631\u0648\u062f\u0647 \u06cc \u0628\u0632\u0631\u06af \u0645\u0634\u0627\u0647\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/p>\n<h2>\u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0627\u062b\u0631:<\/h2>\n<p>\u062f\u0627\u0628\u0631\u0627\u0641\u0646\u06cc\u0628\u060c \u06cc\u06a9 \u062f\u0627\u0631\u0648\u06cc \u062e\u0648\u0631\u0627\u06a9\u06cc \u00a0\u0645\u0647\u0627\u0631 \u06a9\u0646\u0646\u062f\u0647\u200c\u06cc \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 (BRAF) \u0627\u0633\u062a . \u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u0628\u0647 \u0635\u0648\u0631\u062a \u0631\u0642\u0627\u0628\u062a\u06cc \u0648 \u0627\u0646\u062a\u062e\u0627\u0628\u06cc \u0628\u0647 ATP \u00a0\u067e\u0631\u0648\u062a\u0626\u06cc\u0646 BRAF \u0645\u062a\u0635\u0644 \u0645\u06cc\u0634\u0648\u062f \u0648 \u0645\u0627\u0646\u0639 \u0641\u0633\u0641\u0631\u06cc\u0644\u0627\u0633\u06cc\u0648\u0646 \u0627\u0633\u06cc\u062f \u0622\u0645\u06cc\u0646\u0647\u200c\u06cc \u0633\u0631\u06cc\u0646 \u0648 \u062a\u0631\u0626\u0648\u0646\u06cc\u0646 \u0645\u06cc\u200c\u06af\u0631\u062f\u062f \u06a9\u0647 \u0647\u0645\u06cc\u0646 \u0627\u0645\u0631 \u0645\u0648\u062c\u0628 \u06a9\u0627\u0647\u0634 \u062a\u06a9\u062b\u06cc\u0631 \u0633\u0644\u0648\u0644\u06cc \u0627\u0633\u062a \u0639\u0644\u0627\u0648\u0647 \u0628\u0631 \u0627\u06cc\u0646 \u062f\u0631 \u0639\u0631\u0636 24 \u0633\u0627\u0639\u062a \u0628\u0639\u062f \u0627\u0632 \u0645\u0635\u0631\u0641 \u060c \u0645\u06cc\u0627\u0646\u062c\u06cc \u0647\u0627\u06cc \u067e\u0627\u06cc\u06cc\u0646 \u062f\u0633\u062a \u0645\u0633\u06cc\u0631 MAPK \u0647\u0645 \u0645\u0647\u0627\u0631 \u0645\u06cc\u0634\u0648\u0646\u062f .<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"row-277743308\" class=\"row row-full-width align-middle align-center\">\n<div id=\"col-53037258\" class=\"col small-12 large-12\">\n<div class=\"col-inner\">\n<h2>\u0645\u0648\u0627\u0631\u062f \u0645\u0635\u0631\u0641:<\/h2>\n<p>\u0633\u0627\u0632\u0645\u0627\u0646 \u063a\u0630\u0627 \u0648 \u062f\u0627\u0631\u0648\u200c\u06cc \u0622\u0645\u0631\u06cc\u06a9\u0627 (FDA ) \u0627\u062e\u06cc\u0631\u0627 \u062a\u0627\u06cc\u06cc\u062f\u06cc\u0647 \u062a\u0631\u06a9\u06cc\u0628 \u062f\u0627\u0631\u0648\u06cc \u062f\u0627\u0628\u0631\u0627\u0641\u0646\u06cc\u0628 \u2013 \u062a\u0631\u0627\u0645\u0627\u062a\u0646\u06cc\u0628 \u0631\u0627 \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u0627\u0641\u0631\u0627\u062f\u06cc \u06a9\u0647 \u0628\u0647 \u0627\u0646\u0648\u0627\u0639 \u062e\u0627\u0635\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646 \u067e\u06cc\u0634\u0631\u0641\u062a\u0647 \u06a9\u0647 \u0633\u0644\u0648\u0644 \u0647\u0627\u06cc \u0622\u0646\u200c\u0647\u0627 \u062f\u0686\u0627\u0631 \u062c\u0647\u0634 \u00a0BRAFV600E \u0647\u0633\u062a\u0646\u062f\u060c \u0627\u0639\u0644\u0627\u0645 \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a \u0627\u0632 \u062c\u0645\u0644\u0647 \u0627\u06cc\u0646 \u0633\u0631\u0637\u0627\u0646 \u0647\u0627 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u0631\u06cc\u0647 \u060c \u0645\u0644\u0627\u0646\u0648\u0645\u0627 \u0648 \u0633\u0631\u0637\u0627\u0646 \u062a\u06cc\u0631\u0648\u0626\u06cc\u062f \u0622\u0646\u0627\u067e\u0644\u0627\u0633\u062a\u06cc\u06a9 ( \u06cc\u06a9 \u0633\u0631\u0637\u0627\u0646 \u0628\u0633\u06cc\u0627\u0631 \u062a\u0647\u0627\u062c\u0645\u06cc \u0627\u0633\u062a \u062f\u0631 \u06a9\u0645\u062a\u0631\u06cc\u0646 \u0632\u0645\u0627\u0646 \u0645\u0645\u06a9\u0646 \u06af\u0633\u062a\u0631\u0634 \u067e\u06cc\u062f\u0627 \u0645\u06cc\u200c\u06a9\u0646\u062f ) \u0627\u0634\u0627\u0631\u0647 \u06a9\u0631\u062f<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"featured_media":3467,"template":"","product-cat":[41],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.7 (Yoast SEO v22.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u062f\u0627\u0628\u0631\u0627\u0641\u0646\u06cc\u0628 \u0645\u0632\u06cc\u0644\u0627\u062a | \u0634\u0631\u06a9\u062a \u0641\u0646\u0627\u0648\u0631\u0627\u0646 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0631\u0634\u062f \u067e\u0627\u0631\u0633\u06cc\u0627\u0646<\/title>\n<meta name=\"description\" content=\"DABRAFENIB MESYLATE is recognized as a competitive and highly selective inhibitor of BRAF. 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